Method Development
The go to laboratory for new methods!
The industry-leading SGS AXYS team of Ph.D. chemists and research scientists have decades of successful experience developing methods to solve our clients’ unique needs. The quality of our analytical approaches has been recognized by many key agencies and our methods are the backbone of multiple US EPA methods including 1668 for PCBs. We bring this unique ability to deliver validated methods to our industry, government, and academic clients. Most recently, we have introduced exciting ultra-trace GC-MS/MS capabilities to dioxin, PCB and pesticide analysis and are working on validating the isotope dilution method for PFAS analysis in all environmental matrices
Our Capabilities & Approach
We are a full service targeted mass spectrometry method development laboratory. We use our research expertise to review literature for related studies, and we translate that knowledge and our own experience with the compounds or related problems to develop a method that will accomplish the goal. Then we test and optimize each component of the method to ensure its validity and overall performance. We validate and compile that method into the tools necessary to conduct that analysis in a repeatable, defensible manner with QA/QC standards. If required, we seek accreditation for the method. Our analyst team helps you leverage that method to get the data and insights you need from your research initiative. Finally, our scientists regularly collaborate with our clients to produce posters, presentations and peer-review publications on the methods themselves or the innovative projects where they are used.
Our Development History
We have worked successfully with groups in all types of organizations, at all stages of scientific understanding of a particular compound. Here’s just a few examples of the successful development projects under our belt.
Method |
Year |
Remarks |
Isotope Dilution PFAS Method in Aqueous, Solids and Tissue |
2019 In Progress |
Will be the basis of an EPA standard method pending |
Dioxins – GC-MS/MS |
2018 |
In the process of becoming an alternate test method for EPA |
Neonicotinoid pesticides |
2018 |
|
Low level PFAS in AFFF Foam |
2018 |
Future standard published method |
Bisphenols |
2017 |
Expanded suite of bisphenol A and replacement chemistries |
PCBs by GC-MS – EPA Method |
2017 |
Validation of a method for the EPA |
PFAS Total Oxidizable Precursor Analysis (TOP) |
2017 |
|
Current-use brominated and chlorinated flame retardants |
2015 |
|
Organophosphorous flame retardants |
2014 |
|
Targeted Metabolomics |
2014 |
|
Naphthenic acids |
2009 |
|
Multi-residue pesticides |
2005 |
Became EPA-1699 |
Polybrominated Diphenyl Ethers (PBDE) |
2004 |
Became EPA 1614 |
PPCPs |
2003 |
Became EPA 1694 |
PFAS Setup |
2002 |
|
Hormones and sterols |
2001 |
Became EPA 1698 |
PCBs – GC-HRMS |
1991 |
Became EPA 1668 A |
Dioxins – HRMS |
1989 |
|
PCBS – GC-LRMS |
1986 |
Basis of new EPA GC-MS congener method to replace aroclor |